Philipp Kümpers Selected Research

TIE-2 Receptor (Receptor, TIE 2)

11/2019	Tie2 Activation Promotes Protection and Reconstitution of the Endothelial Glycocalyx in Human Sepsis.
2/2018	The curse of angiopoietin-2 in ARDS: on stranger TI(E)des.
5/2012	Angiopoietin-2 levels predict mortality in CKD patients.
8/2011	Acute administration of recombinant Angiopoietin-1 ameliorates multiple-organ dysfunction syndrome and improves survival in murine sepsis.
5/2010	Shedding of the endothelial receptor tyrosine kinase Tie2 correlates with leukemic blast burden and outcome after allogeneic hematopoietic stem cell transplantation for AML.
1/2008	Excess circulating angiopoietin-2 is a strong predictor of mortality in critically ill medical patients.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Philipp Kümpers Research Topics

Disease

18	Sepsis (Septicemia) 11/2022 - 01/2008
12	Critical Illness (Critically Ill) 03/2022 - 01/2008
11	Acute Kidney Injury (Acute Renal Failure) 03/2022 - 01/2010
8	Inflammation (Inflammations) 05/2017 - 10/2007
6	Infections 02/2022 - 01/2009
5	Endotoxemia 12/2012 - 01/2009
4	Chronic Renal Insufficiency 01/2020 - 04/2008
4	Cardiovascular Diseases (Cardiovascular Disease) 01/2017 - 05/2009
4	Multiple Organ Failure (MODS) 05/2012 - 03/2010
3	COVID-19 11/2022 - 11/2021
3	Atherosclerosis 01/2020 - 05/2009
3	Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis 01/2012 - 01/2009
2	Septic Shock (Toxic Shock Syndrome) 12/2021 - 08/2009
2	Vascular Diseases (Vascular Disease) 01/2020 - 05/2012
2	Hypertension (High Blood Pressure) 05/2012 - 08/2009
2	Coronary Disease (Coronary Heart Disease) 05/2012 - 05/2009
2	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 05/2010 - 09/2008
2	Body Weight (Weight, Body) 07/2009 - 04/2008
2	Pneumonia (Pneumonitis) 01/2009 - 03/2008
1	Fatigue 10/2022
1	Cough 10/2022
1	Myalgia 10/2022
1	Anosmia 10/2022
1	Bacteremia 01/2022
1	Cytokine Release Syndrome 12/2021
1	Thrombosis (Thrombus) 12/2021
1	Wounds and Injuries (Trauma) 11/2021
1	Pathologic Neovascularization 11/2021
1	Systemic Inflammatory Response Syndrome (Sepsis Syndrome) 02/2018
1	Pulmonary Embolism 01/2018
1	Venous Thrombosis (Deep-Vein Thrombosis) 01/2018
1	Venous Thromboembolism 01/2018
1	Autosomal Dominant Polycystic Kidney (ADPKD) 01/2018
1	Hyperemia 01/2017
1	Chest Pain (Chest Pains) 03/2016
1	Acute Coronary Syndrome 03/2016
1	Edema (Dropsy) 02/2016
1	Multiple Myeloma 01/2016
1	Disease Progression 01/2015
1	Hemorrhage 01/2015
1	Hemolytic-Uremic Syndrome 01/2015
1	Seizures (Absence Seizure) 01/2015

Drug/Important Bio-Agent (IBA)

20	Angiopoietin-2IBA 12/2021 - 01/2008
12	Biomarkers (Surrogate Marker)IBA 11/2022 - 01/2008
8	Angiopoietin-1IBA 01/2013 - 01/2008
6	Phenobarbital (Luminal)FDA Link 01/2020 - 06/2014
6	TIE-2 Receptor (Receptor, TIE 2)IBA 11/2019 - 01/2008
6	AngiopoietinsIBA 02/2018 - 01/2008
4	EnzymesIBA 01/2022 - 09/2008
4	Proteins (Proteins, Gene)FDA Link 12/2021 - 07/2009
4	CytokinesIBA 11/2021 - 01/2009
4	CarbohydratesIBA 01/2020 - 05/2017
4	C-Reactive ProteinIBA 01/2017 - 07/2009
3	Oxygen (Dioxygen)IBA 10/2022 - 01/2008
3	Anti-Bacterial Agents (Antibiotics)IBA 02/2022 - 01/2017
3	LigandsIBA 02/2018 - 01/2008
3	AlbuminsIBA 02/2016 - 07/2009
2	heparanaseIBA 01/2022 - 11/2019
2	Heparitin Sulfate (Heparan Sulfate)IBA 12/2021 - 11/2019
2	IronIBA 11/2021 - 07/2009
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 11/2021 - 01/2013
2	symmetric dimethylarginineIBA 01/2020 - 01/2017
2	Peptides (Polypeptides)IBA 02/2016 - 06/2011
2	VasculotideIBA 02/2016 - 06/2011
2	Lipocalin-2IBA 02/2014 - 01/2010
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2013 - 01/2009
2	pro-brain natriuretic peptide (1-76)IBA 01/2013 - 04/2008
2	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 01/2013 - 08/2009
2	Antineutrophil Cytoplasmic Antibodies (ANCA)IBA 01/2012 - 01/2009
1	ProteomeIBA 11/2022
1	Biological ProductsIBA 11/2022
1	ElectrolytesIBA 03/2022
1	Heparin (Liquaemin)FDA LinkGeneric 01/2022
1	Pathogen-Associated Molecular Pattern MoleculesIBA 12/2021
1	GlucuronidaseIBA 12/2021
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 11/2021
1	Fibrin Fibrinogen Degradation ProductsIBA 11/2021
1	Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA 11/2021
1	Interleukin-1 (Interleukin 1)IBA 11/2021
1	HDL LipoproteinsIBA 01/2020
1	Membrane Proteins (Integral Membrane Proteins)IBA 01/2018
1	fibrin fragment D (D-dimer)IBA 01/2018
1	Acetylcholine (Acetylcholine Chloride)FDA Link 01/2017
1	Nitroprusside (Sodium Nitroprusside)FDA LinkGeneric 01/2017
1	trans-crotonin (CTN)IBA 03/2016
1	TroponinIBA 03/2016
1	Blood Coagulation Factors (Coagulation Factor)IBA 01/2015
1	Shiga Toxin (Shigella Toxin)IBA 01/2015
1	Human Serum Albumin FDA LinkGeneric 01/2015

Therapy/Procedure

6	Therapeutics 12/2021 - 01/2009
5	Renal Replacement Therapy (Therapies, Renal Replacement) 01/2022 - 01/2010
2	Resuscitation 03/2022 - 11/2021
2	Ligation 12/2021 - 08/2011
2	Critical Care (Surgical Intensive Care) 01/2017 - 01/2010
2	Renal Dialysis (Hemodialysis) 01/2016 - 01/2015
2	Artificial Respiration (Mechanical Ventilation) 01/2015 - 05/2012
2	Kidney Transplantation 01/2015 - 05/2009
2	Hematopoietic Stem Cell Transplantation 05/2010 - 09/2008
1	Liver Transplantation 01/2019
1	Lasers (Laser) 01/2017